Anomalously slow transport in single-file diffusion with slow binding kinetics
نویسندگان
چکیده
منابع مشابه
The kinetics of slow-binding and slow, tight-binding inhibition: the effects of substrate depletion.
Inhibitors with dissociation constants in the micromolar to nanomolar range are important, but hard to characterize kinetically, especially when the substrate concentration in the assay is less than Km. When inhibition increases during the course of the assay (slow-binding inhibition) the concentration of substrate may decrease appreciably. Methods that take substrate depletion into account are...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 2018
ISSN: 2470-0045,2470-0053
DOI: 10.1103/physreve.98.022114